It’s the beginning of a mystery where nothing would be what it seemed... The full story tonight at 9/8c on a classic Dateline. | Dateline NBC

Thursday on a special edition of Dateline at 10/9c, join Lester Holt for an in-depth look at the race for a COVID-19 vaccine. | Dateline NBC

Thank you for watching tonight's Dateline, East Coast and Central! Before you go, Lester Holt has an important announcement... | Dateline NBC

Tonight, Lester Holt tackles the questions we all want answered surrounding the COVID-19 vaccines. We hope you'll join us for a special edition of Dateline at 10/9c. | Dateline NBC

The case shifted from a missing person investigation into a homicide... The full story on Dateline tonight at 9/8c. | Dateline NBC