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  1. PTPRC - Wikipedia

    PTPRC is also known as CD45 antigen (CD stands for cluster of differentiation), which was originally called leukocyte common antigen (LCA). [6] PTPRC is a critical enzyme involved in regulating …

  2. What Are CD45 Positive Cells and Why Do They Matter?

    Nov 16, 2025 · CD45 positive cells carry the Cluster of Differentiation 45 (CD45) protein marker on their surface. This surface marker serves as a universal identification tag for almost every cell …

  3. Pathology Outlines - CD45 (LCA)

    Feb 1, 2022 · CD45 is a ubiquitous cell surface marker of nucleated hematopoietic cells involved in the regulation and activation of the immune system

  4. What is CD45? – MyPathologyReport

    CD45 is a protein found on the surface of most cells in the immune system, including white blood cells (also called leukocytes). CD45 helps these immune cells communicate and respond …

  5. Protein tyrosine phosphatase receptor type C (PTPRC or CD45)

    CD45 is an essential protein on the surface of cells of the haematological and immunological systems. It has been used as a diagnostic tool to identify cells of haematological origin, but its function and …

  6. What Are CD45 Cells and What Is Their Function?

    Jul 23, 2025 · CD45 is a protein found on the surface of nearly all white blood cells, also known as leukocytes. This protein acts as a distinguishing marker, helping to identify these immune cells from …

  7. What Are CD45 Cells and Why Are They Important?

    Learn how CD45 regulates immune system signaling, functions as a critical diagnostic marker, and controls T-cell and B-cell activation.

  8. What Does It Mean to Be CD45 Positive? - Biology Insights

    To be “CD45 positive” means that a specific protein, known as CD45, is present on the surface of a cell. Think of this protein as a uniform worn exclusively by a particular team of cells within the body. …

  9. CD45 in human physiology and clinical medicine - ScienceDirect

    Apr 1, 2018 · CD45 is an evolutionary highly conserved receptor protein tyrosine phosphatase exclusively expressed on all nucleated cells of the hematopoietic system. It is characterized by the …

  10. CD45 in human physiology and clinical medicine - PubMed

    CD45 is an evolutionary highly conserved receptor protein tyrosine phosphatase exclusively expressed on all nucleated cells of the hematopoietic system. It is characterized by the expression of …