Background: In anesthetized patients undergoing surgery, the role of lung-protective ventilation with lower tidal volumes is unclear. We performed a meta-analysis of randomized controlled trials (RCTs ...

Please provide your email address to receive an email when new articles are posted on . Children with asthma and obesity breathe at higher tidal volumes, which may increase the efficiency of ...

A single stretch of alveolar type II cells causes an increase in cytosolic calcium resulting in stimulation of surfactant secretion for up to 30 min post stretch (1). In adult animals, this mechanism ...

There is another potential advantage to the emphysematous patient to be gained from tracheostomy: the reduction of the dead space. This would allow increased alveolar ventilation for the same total ...

Better Outcomes for Ventilation With Lower Tidal Volumes Protective ventilation with lower tidal volumes is associated with better clinical outcomes in patients without acute respiratory distress ...

Please provide your email address to receive an email when new articles are posted on . During the first month of the COVID-19 outbreak in the Netherlands, there was broad use of lung-protective ...

What is patient/ventilator synchrony? Broadly speaking, a patient and ventilator are in synchrony when the settings on the ventilator are matched with what the patient's respiratory system is trying ...

This retrospective study was approved by the institutional review board of Children's Hospital, Boston. All patients aged <19 yrs who were admitted to the 29-bed medical– surgical pediatric intensive ...

The chief reason that patients are admitted to an intensive care unit is to receive ventilatory support. In this article, I update the basic principles of mechanical ventilation, which I reviewed in ...