Raised blood pressure remains the leading modifiable risk factor for cardiovascular disease and premature mortality worldwide, affecting an estimated 1·3 billion adults.1 Although most patients ...

Preliminary studies 12 suggested that in man amphenone is an effective inhibitor of aldosterone synthesis or release. The present report summarizes our experience to date. The white zones are areas of ...

In nine separate studies on four patients with severe pitting edema, aldosterone secretion fell during a 24-hour period of acute salt and water depletion induced by diuretics. These results contrast ...

A drug that has been used to slow progression of kidney and cardiovascular disease in people with type 2 diabetes may also help people with chronic kidney disease who do not have diabetes, according ...

What if there were a straightforward and relatively inexpensive way to lower the incidence of heart failure (HF), renal disease, stroke, and cognitive impairment? Cardiologist Bertram Pitt, MD, said ...

Please provide your email address to receive an email when new articles are posted on . Dysregulated aldosterone production, sometimes driven by obesity, can cause hypertension. Targeted therapies ...

Roughly 16%-22% of patients with hypertension appeared to have primary aldosteronism as the likely major cause of their elevated blood pressure, in an analysis of about 1,000 Americans, which is a ...

Current treatment options for primary aldosteronism are limited to surgery or mineralocorticoid receptor antagonists when surgery isn't an option. In a phase IIa trial, baxdrostat resolved or reduced ...

The coronavirus disease 2019 (COVID-19) pandemic caused millions of deaths throughout the world, which has provoked intense research into the pathogenetic mechanism behind this disease. A new study ...