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Somatic and germline mutation rates covary linearly across ciliates and mammals, study finds

In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences and Prof. Zhang Jianzhi's team at the University ...
Technology Networks

Predictive Tools Can Confuse Rare Mutations With Dangerous Ones

Researchers evaluated 50 leading genetic variant prediction tools and found many systematically overestimate the impact of ...

In 1992, NASA studied C elegans worms exposed to space radiation on IML-1; the experiment reported higher mutation rates than in ground controls

In 1992, micro worms unveiled the troubling effects of space radiation on DNA, showcasing considerable genetic harm to these ...
Nature

Mutation Rate Dynamics in Genetic Systems

Mutation rates govern the introduction of genetic variation and influence evolutionary trajectories, disease susceptibility and species diversity. Rates are shaped by a balance between DNA damage, ...
Phys.org

New technique boosts mutation rates in fruit flies for genetics research

A new technique, TF-High-Evolutionary (TF-HighEvo), allows large-scale assessment of de-novo mutations in multicellular organisms. Developed in collaboration with researchers from the European ...
Nature

Mutation Dynamics in Bacterial Evolution

Mutation dynamics in bacterial populations underpin the generation of genetic diversity that drives adaptation, speciation and the emergence of antimicrobial resistance. Spontaneous base substitutions ...
News Medical

NSF grant supports UH researchers to investigate how mutation rates evolve across species

This mutation rate dictates how quickly species can adapt to changing environments. Supported by a combined $2.08 million in total NSF funding across partner institutions, the multi-institutional ...
News Medical

Study sheds light on the rate and nature of mutations in mitochondrial DNA

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its ...
EurekAlert!

The rate, nature and transmission of mitochondrial DNA mutations in humans

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its ...
ascopubs.org

Mutation rate differences across populations and association with performance disparities in pathology AI diagnostic models.

Community-based patient navigation and preventative care among women surviving breast cancer. Gentian violet compared with methylene blue for sentinel lymph node biopsy in breast cancer: A ...