Loss of Dnmt1 disrupted normal DNA methylation in chondrocytes, leading to increased expression of genes involved in cellular energy metabolism. As a result, metabolic abnormalities occurred, ...

SCFAs promote the production of IGF-1 in the liver and adipocytes, enhancing the proliferation and differentiation of osteoblasts, and stimulating endochondral ossification to promote longitudinal ...

Time to first symptomatic skeletal event, whether including or excluding death, was similar between treatment arms. Most patients did not experience skeletal complications during the follow-up period.

At head of title: Acta Orthopaedica Scandinavica. Supplementum no. XX. siris_sil_246044 ...