Nanofluidics represents a transformative frontier in understanding the behaviour of DNA and semiflexible polymers under extreme confinement. By exploiting nanochannels and other nanoscale ...

Scientists developed a charge-free polymer-DNA complex that boosts cellular DNA uptake 14-fold in mice, avoiding the harmful inflammation caused by current methods.

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

Densely packed polymer chains can spontaneously start moving in one direction, even without being pushed, a finding that could explain DNA behavior and inspire new smart materials.

Polyethyleneimines (PEIs) are extensively researched as non-viral vectors for gene and medication delivery because of their capacity to condense nucleic acids into nanoparticles known as polyplexes. 1 ...

A team led by Professor Shoichiro Asayama at Tokyo Metropolitan University has synthesized a charge-free molecule designed to sneak plasmid DNA into living cells via hydrogen bonding, dramatically ...

Guest molecules slice through droplets of DNA polymers in the form of a frontal wave / Basis for a better understanding of biological processes Researchers at Johannes Gutenberg University Mainz (JGU) ...

Molecular instructions in living cells can be timed rather like the notes or chords in a piece of music. For example, a finite number of genes can be activated and expressed in different orders, for ...