Apical hypertrophic cardiomyopathy is a rare condition where the heart walls thicken at the left ventricle’s apex, making it harder for the ventricle to pump. Symptoms are often vague or absent, but ...

—Dr. Wang spoke to MedPage Today to discuss the diagnosis of apical HCM, and distinct features of this disease subtype. Apical hypertrophic cardiomyopathy (HCM) is a morphological subtype of HCM that ...

Panel A shows a cross-section of a normal heart (top) and an endomyocardial biopsy sample from a normal heart (bottom; with hematoxylin and eosin staining) that shows normal histologic characteristics ...

The Hypertrophic Cardiomyopathy (HCM) Program at University of Utah Health is one of the nation’s few programs for comprehensive HCM evaluation and management. Our multidisciplinary team works ...

HCM is a genetic disease, usually caused by mutations in sarcomere proteins such as myosin, actin, tropomyosin, and myosin-binding protein C.

Treatment sometimes involves an implantable defibrillator. Hypertrophic cardiomyopathy is the most common form of genetic heart disease worldwide. Researchers have estimated that up to 1 in 200 people ...

Future Cardiol. 2013;9(5):697-709. Geometry Asymmetric hypertrophy out of proportion to hypertension Concentric remodeling or hypertrophy Symmetric LV hypertrophy that is proportional to exercise ...

HCM has been identified in 122 countries (representing approximately 90% of the world population), with spontaneous (de novo) mutations probably accounting for this disease burden 11 (Figure 1). It is ...

Background A 42-year-old woman with a 20-year history of obstructive hypertrophic cardiomyopathy was referred for alcohol septal ablation following a worsening of symptoms, which had persisted despite ...

The apical pulse is a pulse site on the left side of the chest over the pointed end, or apex, of the heart. It can indicate potential issues with a person’s heart health. The pulse, or heart rate, is ...

Hypertrophic cardiomyopathy (HCM) is a primary disease of cardiac muscle characterized by a thickening of the left ventricular wall and often predominantly affecting the interventricular septum. This ...