Both allopurinol and febuxostat carry similar, significant increased risks for hypersensitivity reactions compared with colchicine, according to data published in Annals of the Rheumatic Diseases.

Please provide your email address to receive an email when new articles are posted on . “We usually use [allopurinol] to treat gout and prevent gout flares because it lowers the uric acid levels and ...

The comparative efficacy of these therapies has been extended to patients with stage 3 chronic kidney disease, a common comorbidity in gout. Allopurinol and febuxostat are similarly effective in ...

Choi notes that many of these lifestyle changes will not only reduce uric acid levels and the risk of recurrent gout but will also improve the health status of those with comorbidities, particularly ...

100% Response Rate Achieved with All Doses of RDEA594 Combined with Febuxostat or Allopurinol; Serum Uric Acid Levels Reduced by Up to 80% SAN DIEGO, Nov. 8, 2010 ...

Mr. M’s height is 5’9″, weight is 195 lb, body mass index is 28.8 kg/m 2, and BP is 128/78 mm Hg. The left great toe is swollen, warm, erythematous, and tender to touch, with chronic synovial changes.

Matched cohort studies revealed infrequent adverse events (AEs) with either treatment, but the number needed to harm for any AE was more than three times higher with colchicine vs NSAIDs. The ...

Dr. Keith Roach writes a medical question-and-answer column weekdays. Dear Dr. Roach: I am a 71-year-old woman recently diagnosed with gout. I have been put on colchicine and allopurinol. Are these ...

Gout is a painful, acute arthritis, more common in men than women, that classically affects the joint at the base of the big toe, although it sometimes affects other joints. If gout recurs over ...